Deemed ‘forever chemicals’ that are environmentally persistent, PFAS (Per- and poly-fluoroalkyl substances) have increased consumption and its adverse and widespread effects are only getting worse. For decades, PFAS has been used in almost every walk of life like home, food, storage, and personal care, which is what makes its exposure and thus its negative effects very high. There are many sources of exposure, one of them being the water supplies in countries around the world. This ‘contaminated’ water has been repeatedly associated with various health outcomes in humans. PFAS act as endocrine disruptors as they interfere with a woman's reproductive system, specifically the ovary, which may cause great damage to a woman's health. The role of these PFAS affecting the female reproductive system, the main target being the organ, will be the focus of this review. By doing a thorough review of articles via PubMed and Google Scholar, with various search terms like PFA’S, ovarian disorders, endocrine disruptors, ovaries, reproductive system. These were then narrowed down to specific search terms like steroid hormones, menarche, menopause, and ovary and PFA exposure). The literature review suggests that PFAS exposure and presence in follicles are harmful to women. Not only are they found in this follicular fluid but can also pass the blood–follicle barrier. While various studies deemed no results linking PFAS exposure with ovarian disruption, various cross-sectional designed studies had a strong correlation between PFAS and disorders that are a result of ovarian disorders such as early menopause, later menarche, and irregular menstrual cycles, and longer cycle length. Zooming in to the molecular level, various studies have shown have PFAS could diminish ovarian reserve and reduce endogenous hormone synthesis through activating peroxisome proliferator-activated receptors, disrupting gap junction intercellular communication between oocyte and granulosa cells, and inducing thyroid hormone deficiency. The literature published shows a strong correlation between PFAS exposure and ovarian disorders however the evidence is still limited to portraying a cause and effect relationship between the two. Thus, more research on the topic needs to be conducted. The environmental exposure aspect of the disease isn't considered when looking at reproductive disorders by the medical community. Thus, to fully comprehend the potential risks of PFAS on ovarian function, investigations need to be carried out.